Krasnova S.P. Set of syndrome of the raised fatigability at the patients with a combined chronic combined pathology hepatobiliary and gastroduodenal zones (clinical-pathogenetic characteristic, treatment, aftertreatment). – Manuscript. Dissertation for the degree of candidate of medical sciences on in the specialty 14.01.02 – internal diseases. – Lugansk State Medical University, Lugansk, 2003.

In the dissertation the data of complex clinical-laboratory inspection 182 patients with presence of a syndrome of the raised fatigability (SRF) on a background of a chronic combined pathology hepatobiliary and gastroduodenal zones. Studied variants of the course of SRF and feature of character of digestive pathology in it. Is opened pathogenical a role of immune and metabolic violations in development and progressed the service SRF.

Pathogenetically justified inclusion of erbisol in the complex of treatment of patients with SFR on a background of combined digestive pathology in combination with proteflazid (with signs of persistent infection) and eleuterococcus (with predominance of asthenic manifestations of SFR). The proof remission of disease has been achieved in 66,7 % of cases. Fixed expediency immunorehabilitation of the patients with the final phenomena of the service SRF with use manax. Thus during one year in 2,3 times the proof remission of disease and normalization of laboratory parameters was more often kept.

Key words: syndrome of the raised fatigability, chronic combined pathology hepatobiliary and gastroduodenal zones, immunity, metabolism, treatment, rehabilitation, erbisol, eleuterococcus, proteflazid, manax.